Adolpho Lutz? (Brazil, 1908) and Paracoccidioides brasiliensis (Splendore?, 1912; Almeida?, 1930)

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In the meantime, developments also occurred in Brazil. In 1908, Adolpho Lutz, described a fungus that reproduced by multiple budding, and grew as a filamentous microorganism at room temperature.

Alfonso Splendore thoroughly studied the fungus, and considered it an ascomycetous yeast, naming it Zymonema brasilense.

Paulo de Almeida in 1930, characterized the mycosis and its agent, naming it Paracoccidioides brasiliensis [8]. The disease caused by this agent, paracoccidioidomycosis, is the most important systemic mycosis in Latin America [9].

[8] Wanke B, Londero AT. Paracoccidioides immitis. In: Ajello L, Hay RJ, eds. Medical Mycology, Vol 4, Topley & Wilson’s Microbiology and Microbial Infections. London: Arnold, 1998; 395-407.

[9] San-Blas G, San-Blas F. Immune and chemical responses to paracoccidioidomycosis. In: Jacobs PH, Nall L, eds. Fungal Diseaase, Biology, Immunology, and Diagnosis. Marcel Dekker Inc, 1997; 219-235.